Purified anti-Cytochrome c 612301 from BioLegend

Product Specs
ItemPurified anti-Cytochrome c
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number612301
IsotypeIgG1, Kappa
Conjugate/TagUnconjugated
FormatThis antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml
ApplicationsImmunoprecipitation (IP), Immunocytochemistry (ICC), Intracellular Staining for Flow Cytometry (ICFC)
ReactivityMouse, Rat, Human
Quantity25 µg
Clone6H2.B4
HostMouse
Antibody TypePrimary
NCBI Full Gene Namecytochrome c oxidase assembly homolog COX15
Concentration0.50 mg/mL
ImmunogenRat cyt c-OVA
ClonalityMonoclonal
NCBI Gene AliasesCEMCOX2, MC4DN6
TargetCytochrome c

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Combinatorial BCL-2 family expression in Acute Myeloid Leukemia Stem Cells predicts clinical response to Azacitidine/VenetoclaxCancer DiscoveryJune 2, 2023Alexander Waclawiczek, Aino-Maija Leppä, Simon Renders, Karolin Stumpf, Cecilia Reyneri, Barbara Betz, Maike Janssen, Rabia Shahswar, Elisa Donato, Darja Karpova, et al.measured as cytochrome C release using anti-cytochrome C FITC antibody (clone 6H2.B4, BioLegend, cat #612302) via BD FACSymphony A3 Cell Analyzer. DMSO was used as a negative control for cytochrome C retention,

(2) Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensorAutophagyJune 1, 2021Ponsford AH, Ryan TA, Raimondi A, Cocucci E, Wycislo SA, Fröhlich F, Swan LE, Stagi M.primary antibody was from Nanotools (5F10). The anti-CYCS/cytochrome C antibody was from BioLegend (612302). The anti-VPS35 antibody was from Santa Cruz (sc374372). The anti-TFEB and anti-p-RPS6 (Ser233/236)

(3) Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesiclesThe EMBO journalJune 2, 2020Ryan TA, Phillips EO, Collier CL, Jb Robinson A, Routledge D, Wood RE, Assar EA, Tumbarello DA.(610456, 1:250) and GM130 (610823, 1:1,000) from BD Biosciences; HA (901501, 1:500) and Cytochrome c (612302, 1:1,000) from BioLegend; MFN2 (7581, 1:500) and HA (37245, 1:1,000) from Cell Signalling; TOM20 (SC‐11415,

(4) Evidence for macromolecular crowding as a direct apoptotic stimulusJournal of cell scienceMay 11, 2020Rana PS, Kurokawa M, Model MA.(Fremont, CA). The following antibodies were used: mouse anti-cytochrome c (Biolegend; catalog number 612302, Lot B169559), goat anti-mouse–DyLight 488 (Thermo Fisher Scientific; catalog number 35503, Lot OJ92088)

(5) Inflammatory IFIT3 renders chemotherapy resistance by regulating post-translational modification of VDAC2 in pancreatic cancerTheranosticsJanuary 1, 2020Wang Z, Qin J, Zhao J, Li J, Li D, Popp M, Popp F, Alakus H, Kong B, Dong Q, et al.monoclonal anti-O-GlcNAc (Clone, RL2) (Biolegend, 677902), mouse monoclonal anti-cytochrome c (Biolegend, 612302), rabbit monoclonal anti-Bak (Cell signaling, 12105), rabbit monoclonal anti-Bax (Cell signaling, 5023),

(6) Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged MitochondriaDevelopmental cellFebruary 26, 2018Kruppa AJ, Kishi-Itakura C, Masters TA, Rorbach JE, Grice GL, Kendrick-Jones J, Nathan JA, Minczuk M, Buss F.polyclonal antibody to actin (A2066, Sigma-Aldrich, WB 1:2,000), mouse monoclonal to cytochrome c (6H2.B4, 612302, BioLegend, IF 1:200), rabbit polyclonal to DsRed (632496, Clontech Laboratories, IF 1:500, WB 1:1,000),

(7) Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release SiteseNeuroJanuary 1, 2018Cserép C, Pósfai B, Schwarcz AD, Dénes Á.Synaptic Systems, RRID:AB_887873). To visualize CytC, we used a mouse monoclonal antibody (clone 6H2.B4, 612302, Biolegend, RRID:AB_315775). The specificity of this antibody has been previously tested and described

(8) A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondriaThe Journal of cell biologyNovember 6, 2017Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger JR, Moran MF, Rubin LL, Miller FD, Kaplan DR.phospho-JNK (rabbit, WB, 1:500; 4668; Cell Signaling Technology), anti–cytochrome c (mouse, ICC, 1:550; 612302; BioLegend); anti-MKK4 (rabbit, WB, 1:1,000; 9152; Cell Signaling Technology); anti-Ser257/Thr261 phospho-MKK4

(9) Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen speciesJournal of virologyOctober 1, 2011McGuire KA, Barlan AU, Griffin TM, Wiethoff CM.immunoblotted for cathepsin B (Santa Cruz, catalog no. sc-13985) and cytochrome c (BioLegend, catalog no. 612302). Assessment of mitochondrial membrane potential. THP-1 cells were plated in a 96-well plate at 100,000

(10) Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's diseaseAmerican journal of physiology. Endocrinology and metabolismJuly 1, 2011She P, Zhang Z, Marchionini D, Diaz WC, Jetton TJ, Kimball SR, Vary TC, Lang CH, Lynch CJ.

(11) Metabolic and enzymatic characteristics of adult rat liver parenchymal cells in non-proliferating primary monolayer culturesExperimental Cell ResearchOctober 14, 1977Rolf Gebhardt, Peter Bellemann, Dieter Mecke

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Purified anti-Cytochrome c from BioLegend

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Purified anti-Cytochrome c from BioLegend

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